Nucleosides = Base + Sugar
Nucleotides = Base + Sugar +
Phosphate
Different Forms of Nucleotides
The energy released from ATP hydrolysis is used to drive
the phosphorylation of D-gluose (coupled reactions)
ATP as a Chemical Energy Source
Breakage of the Phosphoanhydride
Bond in ATP
Without ATP, the OH
–
group cannot be displaced
This reaction does not occur without ATP because of the
poor leaving group
Phosphoryl Transfer Reaction
Mechanism I
Phosphoryl Transfer Reaction
Mechanism II
Không có nhận xét nào:
Đăng nhận xét